Filaggrin: the invisible architecture of your skin

Filagrina: la arquitectura invisible de tu piel

We see the surface of the skin, but not everything that supports it. Beneath its appearance lies a precise architecture made up of proteins, lipids and water. An invisible balance that allows the skin barrier to remain strong, flexible and capable of retaining moisture.

Within this structure, filaggrin plays an essential role. This is why TR.01 Filaggrin Barrier Booster has been formulated to support its function and provide the skin with the lipids it needs to strengthen its barrier.

Filaggrin: a small protein with an essential function

Filaggrin is a protein found in the outermost layer of the skin. It helps organise its structure and contributes to its strength. As it breaks down, it also gives rise to different components of the Natural Moisturising Factor, the group of substances that helps the skin retain water and maintain the balance of its surface.

It is therefore not simply a matter of supplying moisture from the outside, but of supporting the mechanisms through which the skin generates and retains it. By promoting filaggrin synthesis, a key protein and precursor of the Natural Moisturising Factor, we strengthen the barrier from within its own biological architecture.

Proteins, lipids and water: the balance we cannot see

When we talk about the skin barrier, we tend to think primarily about lipids. They are essential, but they do not work alone.

A strong barrier also needs proteins to organise its structure and components that help maintain hydration. Filaggrin contributes to both processes: it supports the organisation of the skin’s outermost layer and promotes the formation of the Natural Moisturising Factor.

Proteins, lipids and water work together. If any one of these elements falls out of balance, the skin may feel drier, tighter or uncomfortable. Caring for the barrier therefore requires a broader approach that combines hydration, nourishment and structural support.

When this structure remains strong, the skin is also better prepared to face internal factors, such as hormonal changes, and external factors, including cold weather, wind and variations in temperature and humidity.

The formulator’s perspective

“While the industry constantly pursues new and exotic molecules, we often overlook some of the skin’s most fundamental mechanisms. Filaggrin is one of them: a little-known yet essential structural protein. Its role in the formation of the Natural Moisturising Factor makes it a key focus for intelligent skincare seeking to build skin resilience.”

TR.01: formulated around the skin barrier

TR.01 Filaggrin Barrier Booster is based on this comprehensive understanding of the skin. Its formula is designed to support filaggrin, promote the Natural Moisturising Factor and supply skin-compatible lipids. This combination helps preserve hydration while keeping the barrier strong, flexible and comfortable.

Its key ingredients work in a complementary way:

  • Unsaponifiable oils: particularly valuable fractions of plant oils, rich in components that help nourish, protect and strengthen the skin barrier.

  • Olive phytosqualane: a biomimetic lipid with a high affinity for the skin that helps preserve hydration while keeping it supple and comfortable.

  • Upcycled rice bran oil: a plant oil rich in antioxidant compounds and unsaponifiable fractions that helps nourish and protect the skin.

  • Encapsulated hyaluronic acid: incorporated into meadowfoam seed oil to provide hydration within an oil-based formula.

  • Amino acid-derived emollients with a ceramide-like action: they behave in a similar way to the ceramides naturally found in the skin, helping to strengthen the barrier and reduce feelings of dryness.

TR.01 brings together hydration, nourishment and protection in a silky texture that leaves the skin supple and comfortable, without a greasy feel.

Two ways to incorporate TR.01 into your routine

TR.01 can be used as a treatment on its own. Applied to clean skin, it provides nourishment and lipid support to help protect against moisture loss while improving elasticity, suppleness and comfort.

It can also be used as the final serum or as a topper. A few drops applied at the end of the serum stage add a lipid layer that helps seal in hydration and complete the routine. Alternatively, it can be mixed directly with a serum or moisturiser to enrich its texture and adapt the routine to the skin’s needs.

It can be used in the morning, at night or both, applying a small amount with a gentle massage.

Caring for the structure to transform the surface

The strength of the skin begins long before it becomes visible. It begins with the proteins that organise its structure, the lipids that maintain its cohesion and the mechanisms that allow it to retain water.

TR.01 Filaggrin Barrier Booster acts on this invisible architecture with a formula centred on filaggrin, the Natural Moisturising Factor and lipid support. A treatment designed to help the skin remain strong, supple, protected and comfortable.

Frequently asked questions 

What is filaggrin and why is it important for the skin?

Filaggrin is an essential protein found in the outermost layer of the skin. It helps organise its structure and contributes to the formation of the Natural Moisturising Factor, which plays a key role in retaining water and maintaining skin comfort.

Which skin types is TR.01 recommended for?

TR.01 is particularly suitable for dry, sensitive or uncomfortable skin, as well as skin with a compromised barrier. It is also ideal for anyone looking to enhance hydration and add lipid support to their routine.

How should TR.01 be used?

Apply a small amount to clean skin in the morning, at night or both, massaging gently. It can also be mixed with a serum or moisturiser.

Can I combine TR.01 with other serums?

Yes. It can be used as the final serum or as a topper, adding a lipid layer that helps seal in hydration and complete the routine.

Does TR.01 leave the skin feeling greasy?

No. Its silky texture provides nourishment and comfort while leaving the skin supple, without a greasy feel.